What does the odds ratio estimate in a case-control study

Odds ratio epidemiology

A case-cohort design for epidemiologic cohort studies and disease prevention trials. Gail MH. Am Stat Assoc ; — Google Scholar 4. Use of the logistic model in retrospective studies. Chronic disease modelling: Measurement and evaluation of the risks of chronic disease processes. Biometrics ; — If the horse runs races and wins 5 and loses the other 95 times, the probability of winning is 0. When a case-control approach is used for sampling, we don't know how many exposed people it took to generate the 7 cases in the first row, and we don't know how many non-exposed persons were needed to generate the 6 cases in the second row. Interpretation and estimation of summary ratios under heterogeneity. However, for the time being the key things to remember are that: The sampling strategy for a case-control study is very different from that of cohort studies, despite the fact that both have the goal of estimating the magnitude of association between the exposure and the outcome.

Google Scholar What the economist had actually said was, "Whether we reach the technical definition [of a double-dip recession] I think is probably close to A case-cohort design for epidemiologic cohort studies and disease prevention trials.

Statistical methods in cancer research, Vol.

What does the odds ratio estimate in a case-control study

Example: If the probability of an event is 0. The information from non-diseased controls allow us to estimate the exposure distribution in the source population.

Odds ratio case control

Thus the odds ratio should, in general, give way to the incidence ratio and difference as the measures of choice for exposure effect in epidemiology. A case-cohort design for epidemiologic cohort studies and disease prevention trials. Miettinen O, Nurminen M. Design options in epidemiologic research: an update. Case-control studies are particularly useful when the outcome is rare is uncommon in both exposed and non-exposed people. Wacholder S. Rothman KJ.

Biometrika ; 1— Int J Epidemiol ; — Stat Med ; — In other words, I don't know the exposure distribution for the entire source population. What does the odds ratio estimate in a case-control study? However, in certain situations a case-control study is the only feasible study design. A method of estimating comparative rates from clinical data: Applications to cancer of the lung, breast and cervix.

relative risk is the most appropriate measure for cohort studies.

However, the odds ratio can be relinquished as an effect measure for these study designs; and, the application of the case-base sampling approach permits the incidence ratio and difference measures to be estimated without any untenable assumptions.

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To use or not to use the odds ratio in epidemiologic analyses?